Magnetic Resonance Spectroscopy Studies of Cardiac Muscle Metabolism
Recruiting
Observational Study
Heart Failure, Congestive
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 500 (estimated)
- Sponsor
- Johns Hopkins University · Other
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About This Trial
The metabolism of the heart provides the chemical energy needed to fuel ongoing normal heart contraction. Magnetic resonance spectroscopy is a technique used in a MRI scanner that can be used to measure and study heart metabolism directly but without blood sampling or obtaining tissue biopsies. One of the hypotheses this study aims to investigate is whether energy metabolism is reduced in heart fa…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* age \> 18 years
* Healthy subjects: no history of heart disease
* Dilated cardiomyopathy: history of heart failure, ejection fraction (EF) \<40%
* Left ventricular hypertrophy: wall thickness \>1.2cm
* Coronary artery disease: \>50% coronary lesion or positive stress test
Exc…
Contacts