The Pre-symptomatic Familial Amyotrophic Lateral Sclerosis (Pre-fALS) Study

Recruiting Observational Study
Amyotrophic Lateral Sclerosis
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
500 (estimated)
Sponsor
University of Miami · Other
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About This Trial
Pre-fALS is a prospective natural history and biomarker study of people not yet affected with ALS, but who are at genetic risk for developing ALS. The investigators aim to recruit unaffected (healthy) people from familial ALS (fALS) pedigrees in which a known genetic mutation associated with ALS has been identified; for this study, a fALS pedigree is one with two biologically related individuals w…
Trial Locations
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Eligibility Criteria
Inclusion Criteria * A member of a family in which a mutation in a gene associated with ALS has been identified. * No symptoms to suggest the presence of ALS (i.e. study participants must currently be healthy). * Having at least 50% probability of carrying an ALS associated gene mutation based on f…
Contacts

Anne-Laure M Grignon, MD

1-888-413-9315

fals@med.miami.edu

CONTACT