Pyridostigmine for Postural Tachycardia Syndrome
A Study of Pyridostigmine in Postural Tachycardia Syndrome
- Age
- 15 – 55
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 50 (estimated)
- Sponsor
- Mayo Clinic · Other
This trial is looking for people with postural tachycardia syndrome (POTS) to see if pyridostigmine can help. Participants will take pyridostigmine or a placebo for 3 days to compare effects on their symptoms.
You may be able to join if
- I have been diagnosed with postural tachycardia syndrome.
- My heart rate increases by 30 beats per minute or more when I stand up.
- I experience symptoms like weakness, lightheadedness, or palpitations.
You may not be able to join if
- I am pregnant or breastfeeding.
- I have another serious health problem that affects my nervous system.
- I have thyroid problems.
- I have significant coronary artery disease.
- I have taken pyridostigmine for POTS in the last month.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your EligibilityThis is a 3-day study comparing pyridostigmine versus placebo in the treatment of postural tachycardia syndrome (POTS). The researchers expect pyridostigmine to improve tachycardia and stabilize blood pressure.
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