PTGS1 Genetic Variation and Increased Risk for Persistent Pulmonary Hypertension of the Newborn
Recruiting
Observational Study
Persistent Pulmonary Hypertension of the Newborn
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- Up to 12 Months
- Sex
- Any
- Study type
- Observational
- Participants needed
- 200 (estimated)
- Sponsor
- Medical College of Wisconsin · Other
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About This Trial
The purpose of this study is to determine if normally occurring variations in a specific gene called PTGS-1 are associated with an increased risk of narrowing of the ductus arteriosus from exposure to over-the-counter pain medicines (NSAIDs).
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Infants born greater than or equal to 34 weeks gestational age diagnosed with PPHN and normal, healthy infants born greater than or equal to 34 weeks gestational age.
Exclusion Criteria:
* Patients will be excluded if they are diagnosed with lethal congenital anomalies
* str…
Contacts