Cancer Vaccine for Metastatic Cancers
Autologous and Allogeneic Whole Cell Cancer Vaccine for Metastatic Tumors
Recruiting
Phase 1
Phase 2
Interventional Study
Colorectal Cancer
Ovarian Cancer
Gastric Cancer
Breast Cancer
Lung Cancer
Kidney Cancer
Melanoma
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 1/2
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 50 (estimated)
- Sponsor
- Hadassah Medical Organization · Other
Who this trial is looking for
This trial is looking for adults with certain advanced cancers, including melanoma and breast cancer. Participants will receive a modified cancer vaccine through injections to help boost their immune response over eight sessions.
Are You a Good Fit for This Trial?
You may be able to join if
- I have been diagnosed with metastatic cancer like melanoma or breast cancer.
- I am over 18 years old.
- I have not responded to at least one chemotherapy treatment.
- I have a good performance status (ECOG 0 or 1).
- My absolute neutrophil count is greater than 1000/mm3.
- My ALT/AST levels are less than three times the normal limit.
- My creatinine level is 1.6 mg/dl or lower.
- I can understand and sign the Informed Consent document.
You may not be able to join if
- I am under 18 years old.
- I am pregnant.
- My life expectancy is less than three months.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
This study is based on the finding that tumor cells that are grown in the laboratory can be modified in such a way that, when injected to the patient, they will stimulate his/her immune response. This approach will be evaluated in patients with melanoma and colorectal, gastric, ovarian, breast, lung and kidney epithelial cancer. Tumor cells grown in the laboratory will be modified to make them sti…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* One of the following metastatic cancers: Melanoma, breast, ovary, colorectal, gastric, lung or kidney
* Above 18 years of age
* Failure of at least one chemotherapy protocol
* Clinical performance status of ECOG 0,1
* Absolute neutrophil count greater than 1000/mm3
* Serum ALT…
Contacts