Role of Angiogenesis in Dermatologic Diseases: A Potential Therapeutic Target
Recruiting
Observational Study
Dermatologic Diseases
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
16 and older
Sex
Any
Study type
Observational
Participants needed
85 (estimated)
Sponsor
University of California, Irvine · Other
Who this trial is looking for
This trial is looking for adults aged 16 and older who are willing to have a skin biopsy. Participants will provide skin samples that researchers will study to understand blood vessel growth in various skin diseases.
Are You a Good Fit for This Trial?
You may be able to join if
I am 16 years of age or older.
I am willing to have a skin biopsy.
You may not be able to join if
I am under 16 years of age.
I am unable to carry out instructions.
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
The researchers believe that pro-angiogenic factors are upregulated in a wide range of dermatologic diseases, including port wine stains, hemangiomas, angiofibromas, Kaposi's sarcoma, angiosarcoma, scars, rosacea, and psoriasis. Select specimens may undergo genetic analysis to investigate underlying molecular pathways associated with dysregulated angiogenesis in cutaneous disease.
Biospecimens, e…
The researchers believe that pro-angiogenic factors are upregulated in a wide range of dermatologic diseases, including port wine stains, hemangiomas, angiofibromas, Kaposi's sarcoma, angiosarcoma, scars, rosacea, and psoriasis. Select specimens may undergo genetic analysis to investigate underlying molecular pathways associated with dysregulated angiogenesis in cutaneous disease.
Biospecimens, either previously obtained or newly collected from dermatologic conditions, will be analyzed for angiogenic markers. Discarded skin tissue from surgical or biopsy procedures may also be used, including both diseased and non-diseased tissue from the same donor. Some specimens may also undergo genetic analysis to investigate underlying molecular pathways.
De-identified data such as age, sex, race, cause of death, lesion location, and description will be recorded. Currently, specimens are limited to clinically diagnosed lesions not typically biopsied, or lesions already confirmed by prior biopsy.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* 16 years of age or older.
* willing to have a skin biopsy
Exclusion Criteria:
* under 16 years of age
* unable to carry out instructions
Inclusion Criteria:
* 16 years of age or older.
* willing to have a skin biopsy
Exclusion Criteria:
* under 16 years of age
* unable to carry out instructions
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