Factors Affecting Insulin After Gastric Bypass Surgery
Role of Neural and Hormonal Regulation Factors on Insulin Secretion After Gastric Bypass Surgery
Recruiting
Early Phase 1
Interventional Study
Post Bariatricsurgery
Hypoglycemia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 160 (estimated)
- Sponsor
- The University of Texas Health Science Center at San Antonio · Other
Who this trial is looking for
This trial is looking for patients who have had gastric bypass surgery and may have low blood sugar (hypoglycemia). Participants will help researchers understand how certain factors affect insulin release after their surgery.
Are You a Good Fit for This Trial?
You may be able to join if
- I have low blood sugar with levels below 50 mg/dl after gastric bypass surgery.
- I am an asymptomatic person who has had bariatric surgery.
- I am a healthy non-surgical patient with no personal history of diabetes.
- I can visit the clinical research center at Cedars-Sinai Medical Center.
You may not be able to join if
- I have active heart, lung, liver, gastrointestinal, or kidney disease.
- I cannot give consent to participate.
- I am pregnant.
- I have high blood pressure or high cholesterol that is not under control.
- I have significant anemia.
- I have type 2 diabetes.
- I have developed any serious medical or psychiatric illness recently.
- I have gastric outlet obstruction or severe diarrhea if I had gastric bypass surgery.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
RYGB (roux-en-y gastric bypass) has been reported to reverse type 2 diabetes (T2DM) immediately after surgery before any significant weight loss. In addition, a growing number of patients have been recognized with life-threatening hyperinsulinemic hypoglycemia several years following their surgery. While the mechanisms by which RYGB improves glucose metabolism or alters islet cell function in pati…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Hypoglycemic RYGB patients with documented blood glucose level \<50 mg/dl
* Asymptomatic individuals with bariatric surgery
* Healthy non-surgical patients with no personal history of diabetes
* Subjects must physically be able to come to our clinical research center at Cedars…
Contacts