MRI and MRS Techniques for Brain and Muscle Imaging

Development of Magnetic Resonance Spectroscopic Imaging Techniques for Imaging Metabolites in Human Brain and Muscle

Recruiting N/A Interventional Study
Brain Mapping Healthy Volunteer
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 65
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
300 (estimated)
Sponsor
National Institute of Mental Health (NIMH) · NIH
Who this trial is looking for

This trial is looking for healthy volunteers aged 18 to 65 to help researchers improve imaging techniques for studying brain and muscle chemistry. Participants will undergo a health screening and then have MRI and MRS scans to gather data on brain activity.

Are You a Good Fit for This Trial?
Rules you out Multiple sclerosisParkinson's diseaseSeizure disorderTraumatic brain injury

You may be able to join if

  • I am between 18 and 65 years old.
  • I can give written informed consent.
  • I am healthy based on my medical history and physical exam.
  • I am enrolled in Protocol 01-M-0254 or Protocol 17-M-0181.

You may not be able to join if

  • I have a current Axis 1 diagnosis.
  • I have significant laboratory abnormalities.
  • I have a positive HIV test.
  • I have metallic objects in my body that could be affected by MRI.
  • I have a fear of enclosed spaces that prevents me from undergoing an MRI.
  • I have a history of neurological illness or injury.
  • I cannot lie flat on the scanning bed for about two and a half hours.
  • I am pregnant or breastfeeding.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

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About This Trial
Background: \- Magnetic resonance imaging (MRI) is a widely used scanning technique to obtain images of the human body and evaluate activity in the brain. A particular MRI method called magnetic resonance spectroscopy (MRS) can be used to study brain chemistry as well, which may help researchers who are studying new treatments for psychiatric illnesses. Researchers are interested in improving cur…
Trial Locations
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Eligibility Criteria
* INCLUSION CRITERIA: * 18-65 years of age * able to give written informed consent * healthy based on medical history and physical exam * enrolled in Protocol 01-M-0254 or Protocol 17-M-0181 EXCLUSION CRITERIA: * Any current Axis 1 diagnosis * Clinically significant laboratory abnormalities * Posi…
Contacts

Christopher S Johnson

(301) 402-6695

johnsonchri@mail.nih.gov

CONTACT

Li An, Ph.D.

(301) 896-2882

anl@mail.nih.gov

CONTACT