No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
1,200 (estimated)
Sponsor
University of Chicago · Other
Who this trial is looking for
This trial is looking for patients receiving ongoing care at the University of Chicago. Participants will provide DNA samples to help understand how their genes may affect their medication responses.
Are You a Good Fit for This Trial?
You may be able to join if
I am at least 18 years old
I have a life expectancy of at least 3 years
I am receiving ongoing, out-patient care at the University of Chicago
I am taking at least 1 prescription medication or am 65 years or older
I may require medication in the next 5 years
I have heart disease, inflammatory bowel disease, or hepatitis C
I have an autoimmune or inflammatory disease
I require long-term anticoagulation
You may not be able to join if
I have an acute or chronic disease likely to cause death in 3 years
I have undergone or am being considered for a liver or kidney transplant
I cannot understand or give consent to participate
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
The purpose of this study is to collect DNA samples from patients undergoing routine care at the University of Chicago. These samples will be tested for differences in genes that may suggest greater risk of side effects or chance of increased benefit from certain medications. The results will be made available to the patient's treating physician and the researchers will track whether or not this i…
The purpose of this study is to collect DNA samples from patients undergoing routine care at the University of Chicago. These samples will be tested for differences in genes that may suggest greater risk of side effects or chance of increased benefit from certain medications. The results will be made available to the patient's treating physician and the researchers will track whether or not this information is used in routine health care.
Trial Locations
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City
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Status
Eligibility Criteria
Inclusion Criteria:
* Receiving ongoing, out-patient care at the University of Chicago Medical Center under the routine care of a physician participating in this trial
* Life expectancy of at least 3 years
* Must be 18 years or older
* Must be taking at least 1 (but not more than 6) prescription me…
Inclusion Criteria:
* Receiving ongoing, out-patient care at the University of Chicago Medical Center under the routine care of a physician participating in this trial
* Life expectancy of at least 3 years
* Must be 18 years or older
* Must be taking at least 1 (but not more than 6) prescription medications at the time of enrollment OR be 65 years or older OR be reasonably expected to require the use of a prescription medication within the next 5 years
* Patients with certain diseases, or likely to receive or be receiving certain drugs, will be targeted particularly for enrollment in order to enrich the study for patients likely to have pharmacogenetically relevant interactions, including, but not limited to:
* Patients requiring specialized cardiology care
* Patients with inflammatory bowel diseases
* Patients with systemic autoimmune or inflammatory diseases
* Patients requiring long-term oral anticoagulation
* Patients with hepatitis C
* Patients with non-metastatic cancer
Exclusion Criteria:
* Patients with acute or chronic disease which could be reasonably expected to result in the patient's death within the next 3 years.
* Patients who have undergone, or are being actively considered for, liver or kidney transplantation.
* Inability to understand and give informed consent to participate.
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