Hyperpolarized 129Xe MRI for Imaging Pulmonary Function
Recruiting
Phase 2
Interventional Study
Interstitial Lung Disease
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Trial phase
- Phase 2
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 445 (estimated)
- Sponsor
- Bastiaan Driehuys · Other
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About This Trial
The purpose of this study is to develop and evaluate the usefulness of MRI using 129Xe gas for regional assessment of pulmonary function. Specifically, three forms of 129Xe MRI contrast will be the investigators focus - 1) imaging of the 129Xe ventilation distribution, 2) imaging the alveolar microstructure via the 129Xe apparent diffusion coefficient (ADC), and 3) imaging 129Xe that dissolves in …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Inclusion Criteria for Healthy Control Subjects
1. Subject has no diagnosed pulmonary conditions
2. Subject has not smoked in the previous 5 years.
3. Smoking history, if any, is less than or equal to 5 pack-years.
Inclusion Criteria for Subjects with lung disease
1. Subject …
Contacts