Natural History Study - Mitochondrial Disease
Recruiting
Observational Study
MELAS or m.3243 A>G Mitochondrial DNA Mutation Carrier
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 4 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 300 (estimated)
- Sponsor
- Columbia University · Other
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Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Carriers of the m.3242A\>G mutation often have clinical symptoms which can include migraines, seizures, strokes, hearing loss, balance issues, gastrointestinal issues, and many other symptoms. The investigators would like to learn more about these disorders and have designed a "Natural History Study" to monitor these conditions over time so that physicians and scientists can not only understand th…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Known carrier of a the m.3243 A\>G mitochondrial mutation, ,or Maternally related to someone who carries the m.3243A\>G mitochondrial mutation.
A family member who is not maternally related to someone who carries the m.3243A\>G mitochondrial mutation
Exclusion Criteria:
* You…
Contacts