Sympathetic Overactivity in Post-traumatic Stress Disorder
Recruiting
N/A
Interventional Study
Post-traumatic Stress Disorder
Prehypertension
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 120 (estimated)
- Sponsor
- Emory University · Other
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About This Trial
Post-traumatic stress disorder (PTSD) is a highly prevalent anxiety disorder that is associated with an increased risk of cardiovascular (CV) disease and hypertension. One potential mechanism is overactivation of the sympathetic nervous system (SNS), both at rest and particularly during stress. This study will evaluate whether 8 weeks of daily DGB therapy or transcutaneous vagus nerve stimulation …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* prehypertensive and normotensive veterans with PTSD, and prehypertensive and normotensive veterans without PTSD (controls)
Exclusion Criteria:
* heart or vascular disease
* illicit drug use within the last 6 months
* excessive alcohol use (\>2 drinks per day)
* pregnancy
* a…
Contacts
Jeanie Park, MD
404-321-6111
CONTACT