COsegregation of VARiants in Panel of Genes
Recruiting
N/A
Interventional Study
Gene Mutation-Related Cancer
Genetic Predisposition
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 11,000 (estimated)
- Sponsor
- Institut Curie · Other
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About This Trial
The aim of the COVAR project is to achieve reliable classification of as many variants of interest as possible from the French OncoGenetics Database (FrOG, https://frog-db.fr/) in order to use them for the genetic counseling. The results obtained through this study will have a major impact on clinical management of the patients and their families conducting in some cases to propose a prophylactic …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
Index cases:
* A person carrying a variant of interest in a gene analyzed in a diagnostic setting by one of the laboratories within the Genetics and Cancer Group (GGC)-Unicancer network, classified as class 3, 4 or hypomorphic class 5, and selected by the national expert group …
Contacts