Glucagon-like Peptide 1, Glucose Metabolism and Gastric Bypass
Recruiting
Early Phase 1
Interventional Study
Post-bariatric Surgery
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Trial phase
- Early Phase 1
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 80 (estimated)
- Sponsor
- The University of Texas Health Science Center at San Antonio · Other
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About This Trial
The overall goal of this project is to understand the mechanisms by which gastric bypass surgery improves glucose metabolism.
The central hypothesis guiding this project is that the reconfiguration of intestinal transit with the Roux-en-Y will increase the release of insulinotropic GI hormones, termed incretins that improve insulin secretion and glucose metabolism. The study is divided into three…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* age 18-65
* healthy control without diabetes or active organ disease
* Individuals with bariatric surgery
* recurrent hypoglycemia post gastric bypass
Exclusion Criteria:
* pregnancy
* significant anemia
* diabetes currently unless pre-op for bariatric surgery procedure
* GI…
Contacts