Activated T-Cells Expressing 2nd or 3rd Generation CD19-Specific CAR, Advanced B-Cell NHL, ALL, and CLL (SAGAN)

Recruiting Phase 1 Interventional Study
Non-Hodgkin Lymphoma Chronic Lymphocytic Leukemia Acute Lymphocytic Leukemia
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
Up to 75
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Treatment
Participants needed
64 (estimated)
Sponsor
Baylor College of Medicine · Other
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About This Trial
Subjects on this study have a type of lymph gland cancer called Non-Hodgkin Lymphoma, acute lymphocytic leukemia, or chronic Lymphocytic Leukemia (these diseases will be referred to as "lymphoma" or "leukemia"). The lymphoma or leukemia has come back or has not gone away after treatment. The body has different ways of fighting infection and disease. No one way seems perfect for fighting cancers. …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: PROCUREMENT Referred patients (or respective donors) will initially be consented for procurement of blood for generation of the transduced ATL. Eligibility criteria at this stage include: * Diagnosis of recurrent B-cell lymphoma or leukemia (ALL or CLL), or newly diagnosed pat…
Contacts

Carlos A Ramos, MD

832-824-4817

caramos@bcm.edu

CONTACT

Mahshid Azamian

832-512-0690

Mahshid.Azamian@bcm.edu

CONTACT