No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
Ready to participate?
Review the details below, then apply to join this clinical trial.
At a Glance
Age
Up to 80
Sex
Any
Study type
Observational
Participants needed
500 (estimated)
Sponsor
Columbia University · Other
Who this trial is looking for
This trial is looking for children and adults with severe obesity that began before they turned 6 years old. Participants will answer questions about their health and eating habits, have a physical exam, and provide a saliva or blood sample for genetic testing.
Are You a Good Fit for This Trial?
You may be able to join if
I have a BMI greater than the 99th percentile diagnosed before age 6
You may not be able to join if
I have known genetic causes of obesity
I have known endocrine causes of obesity
I have had a neurologic tumor, trauma, or surgery
I have had a prior malignancy or transplant
I have known autoimmune diseases
I have edema of a known or unknown cause
I have had prolonged steroid use
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
This study aims to investigate genetic causes of early childhood obesity.
The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood…
This study aims to investigate genetic causes of early childhood obesity.
The investigators will enroll children and adults with severe early onset obesity (BMI \> 99th percentile) diagnosed prior to 6 years of age. The investigators will ask questions about the health and eating behavior of the participants, and perform a brief physical examination. The investigators will collect saliva or blood to perform genetic testing from the participants and invite family members to enroll in the study.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
\- BMI \> 99th percentile documented at age \< 6 years of age
Exclusion Criteria:
* Known genetic causes of obesity
* Known Endocrine causes of obesity.
* Neurologic tumor, trauma or surgery
* Prior malignancy or transplant
* Known autoimmune diseases
* Edema of a known or unk…
Inclusion Criteria:
\- BMI \> 99th percentile documented at age \< 6 years of age
Exclusion Criteria:
* Known genetic causes of obesity
* Known Endocrine causes of obesity.
* Neurologic tumor, trauma or surgery
* Prior malignancy or transplant
* Known autoimmune diseases
* Edema of a known or unknown cause
* Prolonged steroid use.
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