Reproductive Hormones During Sustained Administration of Kisspeptin

Recruiting N/A Interventional Study
Fertility Disorders Hypothalamic Dysfunction
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 60
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
76 (estimated)
Sponsor
Imperial College London · Other
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About This Trial

We want to find out what happens to reproductive hormone levels; Luteinising Hormone (LH), Follicle Stimulating Hormone (FSH), testosterone and oestradiol when kisspeptin is administered to people for a period of 8 days each month, using either placebo (saline) or kisspeptin in doses of 0.1, 0.3 or 1.0 nmol/kg/hour.

Trial Locations
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Eligibility Criteria
Inclusion criteria: * Aged 18-60 years old * Ability to give informed consent * Secondary hypogonadism (or healthy participant) Exclusion criteria: * anaemia * medical problems such as severe heart, kidney or liver disease * blood donation in the last three months or intention to donate blood wit…
Contacts

ALi Abbara, PhD MRCP

020 8383 3242

ali.abbara@imperial.ac.uk

CONTACT

Debbie A Papadopoulou, BSc MRes

020 8383 3242

d.papadopoulou@imperial.ac.uk

CONTACT