Carotid Artery Stenting for Carotid Artery Diseases

The CREST-2 Registry

Recruiting Observational Study
Carotid Artery Diseases
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 80
Sex
Any
Study type
Observational
Participants needed
8,000 (estimated)
Sponsor
University of Maryland, Baltimore · Other
Who this trial is looking for

This trial is looking for patients with severe carotid artery disease who may have symptoms or might be at risk of symptoms. Participants will receive a treatment called carotid artery stenting and will be monitored for any complications after the procedure.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am between 18 and 80 years old.
  • I have at least 70% narrowing of my carotid artery.
  • I have 50-69% narrowing of my carotid artery and am at high risk for surgery.
  • I have had a transient ischemic attack or a non-disabling stroke recently.
  • I have had transient monocular blindness.

You may not be able to join if

  • I have class IV heart failure.
  • I need constant oxygen therapy for COPD.
  • I have severe liver failure.
  • I have end-stage kidney failure and require dialysis.
  • I have cancer that has spread or am undergoing chemotherapy.
  • I have dementia that is more than mild.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial
The objective of C2R is to promote the rapid initiation and completion of enrollment in the CREST-2 randomized clinical trial (clinicaltrials.gov ID NCT02089217). Patients with severe symptomatic and asymptomatic carotid artery occlusive disease will be treated with carotid artery stenting (CAS) performed by experienced and skilled interventionists. Interventionists' eligibility will be determined…
Trial Locations
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Eligibility Criteria
Inclusion Criteria Asymptomatic patients: Age ≥ 18 and ≤ 80 and any one of the following 1. ≥70% stenosis, standard surgical risk for CEA 2. ≥70% stenosis, high anatomic risk for CEA 3. ≥70% stenosis, high physiologic risk for CEA Symptomatic patients: Symptomatic patients are defined by the fo…
Contacts

Kimberlly A Castro-Roberts, MBA, CCRC

410-706-3941

knordstrom@som.umaryland.edu

CONTACT