Using Microbial Genomics to Elucidate the Source of Central-line Associated Bloodstream Infections

Recruiting Observational Study
Laboratory-confirmed Bloodstream Infection Central Line-associated Bloodstream Infections Mucosal Barrier Injury
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Sex
Any
Study type
Observational
Participants needed
60 (estimated)
Sponsor
Boston Children's Hospital · Other
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About This Trial
Central line-associated bloodstream infections (CLABSIs) are the most common healthcare-associated infection in children and are associated with morbidity and mortality. This study will attempt to identify the source of bloodstream infections (BSIs) in children with CLABSI because we hypothesize that many of the BSIs that are currently classified as CLABSIs are actually laboratory-confirmed bloods…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Hospitalized at Boston Children's Hospital * Central venous catheter of any type including peripherally inserted central catheters (PICC) in any location. * Laboratory-confirmed bloodstream infection (LCBI) diagnosed by a clinical blood culture growing certain Gram-negative ro…
Contacts

Rachel Bernier, MPH

857-218-5348

Rachel.Bernier@childrens.harvard.edu

CONTACT