Low Oxygen Breathing for Limb Mobility After Spinal Injury
Effects of Breathing Mild Bouts of Low Oxygen on Limb Mobility After Spinal Injury
Recruiting
N/A
Interventional Study
Spinal Cord Injuries
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 75
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 44 (estimated)
- Sponsor
- Spaulding Rehabilitation Hospital · Other
Who this trial is looking for
This trial is looking for adults aged 18 to 75 who have suffered a spinal cord injury. Participants will breathe low levels of oxygen for short periods to see if it helps improve movement and recovery.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 75 years old.
- I have been medically cleared to participate.
- My spinal injury is at or below C2 and above T12.
- I have some movement in my legs.
- My injury happened more than 1 year ago.
You may not be able to join if
- I have a severe medical illness.
- I am pregnant.
- I have a history of seizures or brain injury.
- I am currently undergoing physical therapy.
- I have diabetes.
- I have cirrhosis.
- I am allergic to caffeine or NSAIDs.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
Accumulating evidence suggests that repeatedly breathing low oxygen levels for brief periods (termed intermittent hypoxia) is a safe and effective treatment strategy to promote meaningful functional recovery in persons with chronic spinal cord injury (SCI). The goal of the study is to understand the mechanisms by which intermittent hypoxia enhances motor function and spinal plasticity (ability of …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 18 and 75 years (the latter to reduce likelihood of heart disease)
* Medical clearance to participate
* Lesion at or below C2 and above T12 with non-progressive etiology
* Classified as motor-incomplete with visible volitional leg movement
* Injury greater than 1 year
Exc…
Contacts