Active Surveillance for Small Kidney Tumors

The Delayed Intervention and Surveillance for Small Renal Masses (DISSRM) Registry

Recruiting Observational Study
Kidney Neoplasm
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 100
Sex
Any
Study type
Observational
Participants needed
600 (estimated)
Sponsor
Abramson Cancer Center at Penn Medicine · Other
Who this trial is looking for

This trial is looking for adults with small kidney masses to see if watching the tumors is a safe option compared to immediate treatment. Participants will need to follow certain guidelines and timeframes during the study.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have a solid kidney mass that is 4 cm or smaller.
  • I am at least 18 years old.
  • I can read, understand, and sign an informed consent form.
  • I am willing to follow the treatment plan and timeline.

You may not be able to join if

  • I have been diagnosed with another cancer within the last two years.
  • I have any signs that my kidney mass might have spread.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

Retrospective studies indicate that active surveillance for clinically localized, small renal masses (cT1a, \<=4cm) is safe. It is our hypothesis that active surveillance is safe and efficacious when compared prospectively to patients undergoing immediate intervention for their small renal mass.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Must have a solid, enhancing renal mass ≤4cm at its greatest dimension found on incidental scanning in the last 6 months. * Age ≥ 18 and able to read, understand and sign informed consent. * Must be willing to adhere to the treatment algorithm and time constraints therein. Ex…
Contacts

Nirmish Singla

410-502-3692

nsingla2@jhmi.edu

CONTACT

Tina Driscoll

twlajni1@jhmi.edu

CONTACT