Effects of High Altitude on Pregnancy Outcomes
Effects of High Altitude on AMPK Activation
Recruiting
Observational Study
Pregnancy
IUGR
Preeclampsia
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 – 45
- Sex
- Female
- Study type
- Observational
- Participants needed
- 84 (estimated)
- Sponsor
- University of Colorado, Denver · Other
Who this trial is looking for
This trial is looking for pregnant women who are having a scheduled cesarean delivery at high altitude or low altitude in Colorado. Participants will provide tissue samples to help researchers understand how living at high altitudes affects blood flow during pregnancy.
Are You a Good Fit for This Trial?
You may be able to join if
- I am having a cesarean delivery at a scheduled time.
- I am around 39 weeks pregnant.
You may not be able to join if
- I have diabetes or gestational diabetes.
- I have any high blood pressure issues during pregnancy.
- I smoke.
- I am pregnant with more than one baby.
- I have had a preterm delivery.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.
Check Your Eligibility
About This Trial
Pregnancy elicits adaptive changes in uteroplacental blood flow, which are altered at high altitude and may contribute to the observed 3-fold increase in intrauterine growth restriction (IUGR) and preeclampsia (PreE). The investigators propose to collect myometrial, cord blood, and placental tissue samples from women at high altitude (Summit County) and low altitude (Denver) in Colorado in order t…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Women scheduled for cesarean delivery at University of Colorado Hospital (Denver, 1600 m) and St. Anthony's Summit Medical Center (Summit County, 3000 m)
* Cesarean delivery at a prescheduled time without any labor, typically at 39 weeks gestation
Exclusion Criteria:
* Women…
Contacts