Study on Exercise and Blood Pressure in Chronic Kidney Disease

Sympatholysis in Chronic Kidney Disease

Recruiting Phase 1 Interventional Study
Chronic Kidney Disease
Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 75
Sex
Any
Trial phase
Phase 1
Study type
Interventional
Purpose
Basic Science
Participants needed
110 (estimated)
Sponsor
Emory University · Other
Who this trial is looking for

This trial is looking for veterans with chronic kidney disease and kidney transplant recipients to understand their exercise limits and blood pressure changes during activity. Participants will need to exercise on a stationary bicycle as part of the study.

Are You a Good Fit for This Trial?
Must not be taking ClonidineMAOIs
Rules you out Severe anemiaCongestive heart failureDiabetic neuropathy

You may be able to join if

  • I am a veteran with Stage III or IV chronic kidney disease.
  • I am a kidney transplant recipient with some kidney function.
  • I am a veteran aged 18 to 75 without kidney disease as a control.
  • I exercise less than 20 minutes twice a week.
  • I am willing and able to follow the study rules.

You may not be able to join if

  • I have severe chronic kidney disease with very low kidney function.
  • I have metabolic alkalosis with high serum bicarbonate levels.
  • I have ongoing drug or alcohol abuse.
  • I have diabetes-related nerve damage.
  • I have a serious systemic disease affecting my survival.
  • I have severe anemia with low hemoglobin levels.
  • I have congestive heart failure or a low heart function.
  • I am pregnant or planning to become pregnant.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The purpose of this study is to find out why patients with chronic kidney disease (CKD) have poor exercise capacity and what causes an increase in blood pressure during exercise (i.e. increased adrenaline levels, or decreased ability of blood vessels to dilate).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Veterans with Stages III and IV Chronic Kidney Disease (CKD) * Kidney transplant recipients with varying degrees of kidney function * Veterans 18-75 years old, without kidney disease, as study controls * Exercise less than 20 minutes twice per week * Willing and able to cooper…
Contacts

Dana DaCosta

404-727-7762

drdacos@emory.edu

CONTACT

Jeanie Park, MD

404-321-6111

CONTACT