Low-Dose Naltrexone for Complex Regional Pain Syndrome

Low-Dose Naltrexone for the Treatment of Complex Regional Pain Syndrome

Recruiting N/A Interventional Study
Complex Regional Pain Syndrome
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
18 – 70
Sex
Any
Study type
Interventional
Purpose
Treatment
Participants needed
120 (estimated)
Sponsor
Stanford University · Other
Who this trial is looking for

This trial is looking for adults with Complex Regional Pain Syndrome (CRPS) who have had the condition for at least a year. Participants will receive either low-dose naltrexone or a placebo for several weeks and will attend study visits and fill out questionnaires.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have Complex Regional Pain Syndrome in my arms or legs.
  • I have had CRPS for at least 1 year.
  • I have been on stable treatment for my condition for 1 month.
  • I meet the Budapest criteria for CRPS.

You may not be able to join if

  • I am allergic to naltrexone or naloxone.
  • I use prescription opioid pain relievers or illegal opioids.
  • I am currently pregnant or planning to become pregnant.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer a few quick questions to see if you may meet the eligibility requirements.

Check Your Eligibility
About This Trial

The investigators are testing treatment with low-dose naltrexone (LDN) for symptom relief of complex regional pain syndrome (CRPS). Study participants will be randomly assigned to receive either LDN or placebo for a period of several weeks. During this period participants will be asked to attend either in-person or virtual study visits and complete questionnaires.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Upper and/or lower extremity CRPS * On stable treatment for 1 month * CRPS for at least 1 year * Meet the Budapest criteria for CRPS at time of the study. Exclusion Criteria: * Any known allergy to naltrexone or naloxone * Use of prescription opioid analgesics or illegal opi…
Contacts

Birute Gedrimaite

(650) 497-0485

birute@stanford.edu

CONTACT