Imaging Biomarkers for ALS and PLS
Imaging Biomarkers in ALS
Recruiting
Observational Study
Amyotrophic Lateral Sclerosis
Primary Lateral Sclerosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 21 – 75
- Sex
- Any
- Study type
- Observational
- Participants needed
- 30 (estimated)
- Sponsor
- University of Minnesota · Other
Who this trial is looking for
This trial is looking for people with amyotrophic lateral sclerosis (ALS), primary lateral sclerosis (PLS), or healthy individuals to participate in MRI scans. Researchers want to find measurable signs of these diseases.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 21 and 75 years old.
- I am able to give signed consent for the study.
- I have been diagnosed with ALS or PLS.
You may not be able to join if
- I have another neurodegenerative disease like Parkinson's or Alzheimer's.
- I have had a serious unstable medical illness in the last 30 days.
- I cannot stay still in an MRI machine for more than 30 minutes.
- I have a pacemaker or other devices in my body that are not allowed during an MRI.
- I weigh more than 300 lbs.
- I cannot comfortably lie flat for 75-90 minutes.
- I need help walking or climbing stairs, and I am not expected to improve in the next year.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
The purpose of the study is to determine if we are able to find one or more biomarkers of Amyotrophic Lateral Sclerosis (ALS) and Primary Lateral Sclerosis (PLS) using magnetic resonance imaging (MRI) scans at different levels, 3 tesla (3T) and 7 tesla (7T). A biomarker is a measurable characteristic that can be used as an indicator of a particular disease state. Identifying biomarkers of a diseas…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* 21 to 75 years of age inclusive.
* Willing and able to give signed informed consent that has been approved by the Institutional Review Board (IRB).
ALS patients:
* A clinical diagnosis of possible, laboratory-supported probable, probable, or definite ALS, according to a modi…
Contacts