Weight Loss or Exercise for Type 2 Diabetes and Heart Health
Diabetes Interventional Assessment of Slimming or Training to Lessen Inconspicuous Cardiovascular Dysfunction
Recruiting
N/A
Interventional Study
Diabetes
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 65
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 120 (estimated)
- Sponsor
- University of Leicester · Other
Who this trial is looking for
This trial is looking for adults with type 2 diabetes to understand how weight loss or exercise can improve heart function. Participants will follow a low-calorie diet or an exercise program and undergo tests to monitor their heart health.
Are You a Good Fit for This Trial?
You may be able to join if
- I am between 18 and 65 years old
- I have been diagnosed with type 2 diabetes for at least 3 months
- My HbA1c is 9% or less on triple therapy, or 10% or less on diet and exercise or other treatments
- I have a body mass index (BMI) over 30 or over 27.5 if I am South Asian
- I was diagnosed with type 2 diabetes before age 60
- I can provide informed consent
- I am currently managing my diabetes with certain glucose-lowering therapies
You may not be able to join if
- I have had diabetes for more than 12 years
- I take more than three different glucose-lowering medications
- I have lost more than 5 kg in the last 6 months
- I have stage 4 or 5 chronic kidney disease
- I am currently using insulin or certain other medications
- I have untreated thyroid disease
- I have known heart disease or heart failure
- I have significant difficulty exercising
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
There is an epidemic of type 2 diabetes in younger adults. These patients are at very high lifetime risk of heart-related complications. Subtle heart abnormalities can be present even at a young age in these patients and may predispose them to heart failure and ultimately premature death. There is emerging evidence that type 2 diabetes can be reversed with weight loss. We propose that weight loss …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Capacity to provide informed consent before any trial-related activities
* Established T2DM (≥3months)
* HbA1c ≤ 9% if on triple therapy or ≤ 10% on diet \& exercise or monotherapy or dual therapy
* Current glucose lowering therapy either mono, dual or triple of any combinatio…
Contacts