Study on Inflammation and Recovery After Cardiac Arrest
Immunoinflammatory Response in Post Cardiac Arrest Syndrome (PCAS)
Recruiting
Observational Study
Cardiac Arrest
Inflammation
Obesity
Hypoxic Ischemic Encephalopathy (HIE)
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 400 (estimated)
- Sponsor
- MaineHealth · Other
Who this trial is looking for
This trial is looking for adults who have been unresponsive after a cardiac arrest and are now in the intensive care unit. Participants will have their blood collected and analyzed for 7 days to help understand how inflammation affects recovery.
Are You a Good Fit for This Trial?
You may be able to join if
- I am 18 years or older
- I have been admitted to the intensive care unit after cardiac arrest
- I am unresponsive after resuscitation
You may not be able to join if
- I am actively dying at the time of evaluation
- I cannot provide consent within 24 hours of resuscitation
- My hemoglobin is less than 7.0 g/dL
- I have active high-volume bleeding
- I require a transfusion
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
This is a prospective, observational study to investigate molecular mechanisms mediating the systemic inflammatory process, and changes to metabolism, and their impact on brain injury, survival, and functional outcomes after cardiac arrest. Investigators have shown that cardiac arrest induces changes in the numbers and properties of circulating immune cells, shifting the balance towards a pro-infl…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Aged 18 years or older
* Admitted to the intensive care unit after cardiac arrest episode
* Unresponsive after resuscitation
Exclusion Criteria:
* Moribund / actively dying at the time of evaluation
* Informed consent cannot be obtained within 24 hours of resuscitation
* Hem…
Contacts