Response of the Myocardium to Hypertrophic Conditions in the Adult Population
Recruiting
Observational Study
Left Ventricular Hypertrophy
Hypertension
Myocardial Fibrosis
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 21 – 99
- Sex
- Any
- Study type
- Observational
- Participants needed
- 2,000 (estimated)
- Sponsor
- National Heart Centre Singapore · Other
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About This Trial
Hypertension and aortic stenosis are the two leading conditions that cause thickening of the heart muscles (left ventricular hypertrophy). Left ventricular hypertrophy is initially adaptive to maintain optimal heart function. Ultimately, heart failure occurs as a result of progressive muscle cell death and scarring (myocardial fibrosis). Dedicated techniques using cardiovascular magnetic resonance…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
1. 21 years and over
2. Physician diagnosed essential hypertension, on at least 1 medication for blood pressure control
3. Newly diagnosed hypertension: systolic blood pressure 140mmHg or greater (diastolic blood pressure 90mmHg or greater) on at least 2 office visits (Weber 201…
Contacts