Optune Delivered Electric Field Therapy and Bevacizumab in Treating Patients With Recurrent or Progressive Grade 2 or 3 Meningioma

Recruiting Phase 2 Interventional Study
Anaplastic (Malignant) Meningioma Atypical Meningioma Grade II Meningioma Grade III Meningioma Recurrent Meningioma Supratentorial Meningioma
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
18 and older
Sex
Any
Trial phase
Phase 2
Study type
Interventional
Purpose
Treatment
Participants needed
27 (estimated)
Sponsor
Northwestern University · Other
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About This Trial
The purpose of this research study is to determine the effects bevacizumab (the study drug) combined with Optune (the study device) tumor treatment field therapy has on meningiomas. Bevacizumab is considered investigational because the US Food and Drug Administration (FDA) has not approved its use for the treatment of meningiomas. The study drug is a medication that blocks the growth of new blood …
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Patients must have a histologic diagnosis of meningioma, World Health Organization (WHO) grade 2 or 3 (atypical or anaplastic) * Patient's tumor must have a supratentorial component * Patients must have measurable or non-measurable (evaluable) disease recurrence; recurrence mu…
Contacts

Study Coordinator

(312)695-1301

cancertrials@northwestern.edu

CONTACT