Cohort Biomonitoring Study to Evaluate the Biocompatibilty of Resin-based Dental Materials
Recruiting
N/A
Interventional Study
Materials Testing
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Health Services Research
- Participants needed
- 100 (estimated)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Other
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About This Trial
Adult patients who require multiple dental restorations will be included in this study. Urine and saliva samples will be taken for determination of bisphenol A levels at several time points, and for analysis of the estrogenic activity using ERE-CALUX.
Also buccal cells will be taken. Next, DNA extraction will be done with a commercial kit. We will determine global alterations in DNA methylation a…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Caucasian, adults,
Exclusion Criteria:
* acute or chronic medical condition, presence of oral inflammatory conditions during the previous 2 weeks, chronic disease requiring intake of drugs, exposure to diagnostic X-rays in the previous 2 months, smoking and consumption of al…
Contacts
No contact information available.