Glass-Ionomer vs Resin-Based Dental Materials
RCT to Evaluate Biocompatibility of Resin-based Dental Materials
Recruiting
N/A
Interventional Study
Materials Testing
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 4 – 10
- Sex
- Any
- Study type
- Interventional
- Purpose
- Health Services Research
- Participants needed
- 200 (estimated)
- Sponsor
- Universitaire Ziekenhuizen KU Leuven · Other
Who this trial is looking for
This trial is looking for people with dental cavities in their primary molars. Participants will help researchers compare two dental materials and provide samples of saliva, urine, and cells from the mouth for further testing.
Are You a Good Fit for This Trial?
You may be able to join if
- I have one or more carious lesions in my primary molars.
You may not be able to join if
- I have carious lesions that have affected the dental pulp.
- I have large dental lesions that need cusp replacement.
- I had oral inflammatory conditions in the past 2 weeks.
- I wear a fixed or removable prosthesis or orthodontic appliance.
- I have a chronic disease that requires me to take drugs.
- I was exposed to diagnostic X-rays in the past 2 months.
- I have had previous dental restorations.
Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.
Think this trial could be right for you?
Answer a few quick questions to see if you may meet the eligibility requirements.
Check Your Eligibility
About This Trial
In this randomized clinical trial, the bio-compatibility of 2 materials used for dental restorations will be compared: glass-ionomer vs resin-based composites.
Urine and saliva samples will be taken for determination of bisphenol A levels at several time points, and for analysis of the estrogenic activity using ERE-CALUX.
Also buccal cells will be taken. Next, DNA extraction will be done with a …
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* one or more carious lesions in primary molars that require treatment
Exclusion Criteria:
* carious lesions that already affected the dental pulp, large lesions requiring cusp replacement, presence of oral inflammatory conditions during the previous 2 weeks, carriage of a fix…
Contacts
No contact information available.