Taste Physiology in Obese Volunteers Before and After Bariatric Surgery
Recruiting
N/A
Interventional Study
Obesity
At a Glance
- Age
- 18 – 55
- Sex
- Any
- Study type
- Interventional
- Purpose
- Basic Science
- Participants needed
- 16 (estimated)
- Sponsor
- University Hospital, Basel, Switzerland · Other
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About This Trial
The objective is to investigate neuro-anatomical correlates of gastrointestinal taste stimulation by means of functional MRI before and after bariatric surgery. Intragastric administration of glucose, monosodium glutamate, chloroquine and placebo is followed by functional brain MRI in obese humans before and 3 months after surgery.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* morbidly obese patients (BMI min 35kg/m2) scheduled for bariatric surgery
* right handed
Exclusion Criteria:
* cardiovascular disease
* neurologic/psychiatric disorders
Contacts