Cystic Fibrosis Research for CFTR Modulator Response

Surrogate Markers of Response to New Therapies in Cystic Fibrosis Patients

Recruiting N/A Interventional Study
Cystic Fibrosis
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Sex
Any
Study type
Interventional
Purpose
Basic Science
Participants needed
75 (estimated)
Sponsor
Hôpital Necker-Enfants Malades · Other
Who this trial is looking for

This trial is looking for cystic fibrosis patients to help understand how well certain biological markers can predict responses to treatments. Participants may or may not be currently treated with CFTR modulators.

Are You a Good Fit for This Trial?

You may be able to join if

  • I have cystic fibrosis and am treated with a CFTR modulator
  • I have cystic fibrosis and am not treated with a CFTR modulator
  • I have a suspected diagnosis of cystic fibrosis but tests ruled it out

You may not be able to join if

  • I am pregnant or breastfeeding
  • I cannot have a nasal swab
  • I cannot have a rectal biopsy

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

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About This Trial

The purpose of this study is to determine which biological marker, or association of biological markers, best predict clinical response of cystic fibrosis patients to CFTR modulators.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Cystic fibrosis patients treated by CFTR modulators (Ivacaftor or the association Ivacaftor-Lumacaftor) * Cystic fibrosis patients non treated by CFTR modulators * Patients in whom cystic fibrosis diagnosis has been suspected, but excluded by physiological and genetic investig…
Contacts

Isabelle Sermet, MD, PhD

33 1 44 49 48 87

isabelle.sermet@aphp.fr

CONTACT

Jean-Louis Pérignon, MD, PhD

jean-louis.perignon@aphp.fr

CONTACT