Sodium Deposition in Soft Tissues of Patients with Kidney Disease
Recruiting
Observational Study
Haemodialysis Complication
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 6 and older
- Sex
- Any
- Study type
- Observational
- Participants needed
- 400 (estimated)
- Sponsor
- Chris McIntyre · Other
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About This Trial
Sodium (Na+) hemostasis is abnormal in CKD patients, and this element can be deposited in the skin, muscle, and skeleton - to cope with long term sodium loading. It is known that sodium stored in this non-osmotically active way, is profoundly inflammatory. Furthermore, inflammation has been associated with several uremic symptoms. The investigators will use novel Na+ MRI imaging to examine the Na+…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age greater than or equal to 6 years
* For patients on maintenance hemodialysis or peritoneal dialysis: more than 3 months duration of therapy
* For patients with CKD stage 1-5: CKD stage 1-5 and no indications to start dialysis
* For heart failure patients: with or without re…
Contacts