Monocyte Profiles in Critically Ill Patients With Pseudomonas Aeruginosa Sepsis

Recruiting Observational Study
Pseudomonas Infections Pseudomonas Septicemia Pseudomonas; Pneumonia Pseudomonal Bacteraemia Pseudomonas Urinary Tract Infection Pseudomonas Gastrointestinal Tract Infection Sepsis Sepsis, Severe Critically Ill
Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 90
Sex
Any
Study type
Observational
Participants needed
100 (estimated)
Sponsor
University of Ulm · Other
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About This Trial

The present study focuses on patients with Pseudomonas aeruginosa (PSA) sepsis. The aim of the present study is to find out whether the M1 (pro-inflammatory) or M2 (anti-inflammatory) phenotype predominates in blood monocytes in critically ill patients with PSA-sepsis, and whether the severity of sepsis and outcome is associated with distinct monocyte phenotype and function.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * age \> 18 years * critically ill patients with sepsis * microbiologically proven infection with Pseudomonas aeruginosa Exclusion Criteria: * life expectancy \< 24 hours * participation in other studies
Contacts

Manfred Weiss, MD, MBA

+49 731 500 60226

manfred.weiss@uniklinik-ulm.de

CONTACT

Eberhard Barth, MD

+49 731 500 60050

eberhard.barth@uniklinik-ulm.de

CONTACT