Use of Adenosine to Determine the Electrophysiological Mechanism of Premature Ventricular Contractions
Recruiting
Phase 4
Interventional Study
Premature Ventricular Contraction (PVC)
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Prior Safety Data
This treatment has already been tested in at least one earlier human trial.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Trial phase
- Phase 4
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 100 (estimated)
- Sponsor
- Weill Medical College of Cornell University · Other
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About This Trial
Unblinded, controlled, non-randomized, mechanistic study to determine whether physiological mechanisms underlying PVC are sensitive to adenosine. One hundred subjects undergoing clinically-indicated, standard-of-care cardiac electrophysiology study (EPS) procedure for PVCs will receive adenosine and/or verapamil to learn if their arrhythmias are inducible similarly to sustained ventricular tachyca…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Diagnosis of premature ventricular contractions (PVCs)
* Scheduled to undergo an electrophysiology study with the intention of performing cardiac ablation for the treatment of PVCs
* Male or female between the ages of 18 and 70 years
* Capable of giving informed consent
Exclu…
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