Cerebral Blood Flow and Ventilatory Responses During Sleep in Normoxia and Intermittent Hypoxia

Recruiting Phase 1 Phase 2 Interventional Study
Obstructive Sleep Apnea of Adult Hypoxia, Brain Sleep Apnea Sleep Disorder Stroke Blood Pressure Endothelial Dysfunction Oxidative Stress
Prior Safety Data This treatment has already been tested in at least one earlier human trial. Healthy Volunteers Welcome You do not need to have the condition being studied to take part.
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At a Glance
Age
18 – 45
Sex
Any
Trial phase
Phase 1/2
Study type
Interventional
Purpose
Basic Science
Participants needed
12 (estimated)
Sponsor
University of Calgary · Other
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About This Trial

A prospective double blind, placebo-controlled, randomized cross-over trial to evaluate the effect of lowering cerebral blood flow on the ventilatory chemoreflexes (acute hypoxic and hypercapnic ventilatory responses).

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Healthy adults * 18 - 45 years of age * Living in Calgary for the past one year * Have no medical condition or should not be taking any blood pressure medications. * The participant should not be lactose intolerant Exclusion Criteria: * Cerebrovascular, cardio-respiratory, r…
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