Impact of the DROP Program on the DRP (Drug Related Problems) Related to Oral Anticancer Drugs in Ambulatory Patients with Risk Factors

Inclusion Criteria: * Patient aged 18 years old or more * With cancer * For wich the initiation or change of an oral anticancer drug is prescribed * With life expectancy estimated to be 6 months or more, in the opinion of the investigator * Of which the treatment with oral anticancer medication is estimated to be 6 months or more in the opinion of the oncologist * Benefiting from an initiation or a change of oral anticancer agents according to the MA: cytotoxic agent, targeted therapy, hormonal therapy (excluding adjuvant treatments); * of which the oral anticancer drug is delivered in pharmacy of town or in retrocession hospital; * With ambulatory status (not hospitalized for the management and treatment ) * Taking 5 or more drugs, including the oral anticancer treatment, and / or treated with an oral anticancer drug requiring complex regimen (combination of 2 oral anticancer drugs, or sequential rate of intake, or associated to intravenous chemotherapy) * With a sufficient autonomy for the management of medication at home * Without either cognitive disorders or major psychiatric disorders, in the opinion of the investigator * Ability to read, write and understand the French language * Having given his written consent to participate in the study * Patient affiliated to the social security scheme or equivalent Exclusion Criteria: * Pregnant or lactating woman * Patient on anti-PD1, anti-PDL-1 or anti-CTLA4-4 immunotherapy concomitant with oral anticancer treatment * Patient under radiotherapy concomitant treatment with oral anticancer * Oral anticancer agent prescribed in a delivery circuit as part of an ATU or clinical trial; * Patient with significant cognitive or psychiatric disorders, in the opinion of the investigator; * Management of drug treatment at home is performed exclusively by the caregiver; * Not having declared a doctor; * Not having a usual city pharmacy, or reporting 2 or more usual city pharmacies; * Patient who has already benefited from a therapeutic education program * In institution or guardianship, major protected by the Law.