Determination of Factors Involved in the Regulation of Immune Responses After Allogeneic Hematopoietic Stem Cell Transplantation
Recruiting
N/A
Interventional Study
Allogeneic Hematopoietic Stem Cell Transplantation
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 and older
- Sex
- Any
- Study type
- Interventional
- Purpose
- Other
- Participants needed
- 700 (estimated)
- Sponsor
- Central Hospital, Nancy, France · Other
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About This Trial
The study concerns donors and patients receiving allogeneic stem cell haematopoietic transplantation. The aim of the study is to analyse HSC graft content in immune effector T (naive, memory, activated, exhausted) and immunoregulatory cell subtypes (Tregs, iNKT, MDSC) and correlate the results with post-transplant immune reconstitution of those different cell subtypes and clinical events (graft-ve…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* patient of the Nancy CHRU, for whom a CSH allograft is planned. or
* hematopoietic stem cell donors received at Nancy's CHRU for the duration of the research
Exclusion Criteria:
* Positive HIV
* active hepatitis B or C infection
Contacts