Tau PET in Imaging and Cognition: Healthy Adults From 55-90
Recruiting
Observational Study
Mild Cognitive Impairment
Aging
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
At a Glance
- Age
- 55 – 90
- Sex
- Any
- Study type
- Observational
- Participants needed
- 105 (estimated)
- Sponsor
- Yaakov Stern · Other
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About This Trial
The investigators aim to use the new PET radioligand, 18F-MK-6240, to detect tau pathology in cognitive healthy and mild cognitive impairment (MCI) elders. The investigators will then examine the interactions between differential tau burden and performance on cognitive tasks, functional magnetic resonance imaging (fMRI) neural activation patterns, and other cognitive and behavioral measures. By in…
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Aged 55-90
* Previously received an amyloid PET scan
* Residing near Columbia University Medical Center
* Must be willing and able to participate
Exclusion Criteria:
* Have a contraindication to PET (e.g, metallic implants, pacemaker, claustrophobia, or cannot lie flat for o…
Contacts