In Vivo Assessment of Glutamine Utilization by Bone Marrow Plasma Cells
Recruiting
N/A
Interventional Study
Healthy
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 60
- Sex
- Any
- Study type
- Interventional
- Purpose
- Diagnostic
- Participants needed
- 20 (estimated)
- Sponsor
- Mayo Clinic · Other
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About This Trial
This pilot study will first establish the feasibility of an in vivo methodology of assessing the utilization of glutamine into the TCA cycle of normal bone marrow plasma cells from healthy subjects while comparing it to an ex vivo approach
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Ages 18-60
* Able to provide written consent
Exclusion Criteria:
* Renal Failure
* Pregnancy
* Active steroid use
* Active liver Disease
* Anemia (Hemoglobin \< 12.5 g/dL in men and \< 11.5 g/dL in women)
* H/O alcohol use (average \> 2 drinks per day)
* BMI \> 30
Contacts