Genetic Risk Testing for Breast Cancer in Women

Responses to Genetic Risk Modifier Testing Among Women With Pathogenic Variants in Breast Cancer Predisposition Genes

Recruiting Observational Study
Genetic Testing BRCA1/2
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
Ready to participate?

Review the details below, then apply to join this clinical trial.

At a Glance
Age
25 and older
Sex
Female
Study type
Observational
Participants needed
806 (estimated)
Sponsor
Memorial Sloan Kettering Cancer Center · Other
Who this trial is looking for

This trial is looking for women with certain genetic mutations related to breast cancer. Participants will respond to tests that help understand their healthcare decisions.

Are You a Good Fit for This Trial?

You may be able to join if

  • I am a female, 25 years or older.
  • I have a confirmed BRCA1 or BRCA2 mutation.
  • I have never had breast cancer.
  • I can communicate in English.
  • I have a confirmed pathogenic variant in specific breast cancer genes in Phase 2.

You may not be able to join if

  • I have had any breast removal surgery to prevent cancer.
  • I have a serious psychiatric illness that prevents me from participating.
  • I cannot follow the study procedures as required.
  • I participated in the first phase of this trial.

Summarized in plain language from this trial's official eligibility criteria. The full criteria are further down this page — only the research team can confirm whether you qualify.

Think this trial could be right for you?

Answer three quick questions written from this study's own rules to see if you may qualify. No account needed to find out.

Check Your Eligibility
About This Trial

The purpose of this study is to describe how women with BRCA1/2 mutations react to genetic risk modifier testing, and to examine how they make decisions about their healthcare.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: Phase I: * Female patient, age 25 years or older (given that women under this age are not generally recommended to receive BRCA1/2 genetic testing) * Completed full sequence or targeted genetic testing with a clinically confirmed BRCA1 or BRCA2 deleterious mutation identified *…
Contacts

Jada Hamilton, PhD, MPH

646-888-0049

hamiltoj@mskcc.org

CONTACT

Mark Robson, MD

646-888-5486

CONTACT