Dystonia Genotype-Phenotype Correlation

Recruiting Observational Study
Dystonia Dystonia; Idiopathic Dystonia, Primary Dystonia, Secondary Dystonia, Familial Dystonia Disorder Dystonias, Sporadic Dystonia; Orofacial Dystonia Lenticularis Dystonia, Paroxysmal Dystonia 6 Dystonia 5 Dystonia 8 Dystonia 9 Dystonia 19 Dystonia 10 Dystonia 11 Dystonia 20 Dystonia 12 Dystonia, Focal Dystonia of Head Dystonia, Diurnal
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Healthy Volunteers Welcome You do not need to have the condition being studied to take part. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
11 and older
Sex
Any
Study type
Observational
Participants needed
200 (estimated)
Sponsor
University of Texas Southwestern Medical Center · Other
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About This Trial
The purpose of this study is to (1) investigate the effect of known dystonia-causing mutations on brain structure and function, to (2) identify structural brain changes that differ between clinical phenotypes of dystonia, and to (3) collect DNA, detailed family history, and clinical phenotypes from patients with idiopathic dystonia with the goal of identifying new dystonia-related genes. Investiga…
Trial Locations
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Eligibility Criteria
General Exclusion (both Dystonia and Control groups): * Metal in any part of the body (including metal injury to the eye) OR carrying a medical device incompatible with MRI (e.g., metal implants such as surgical clips or pacemakers) OR positive screening per UTSW MRI screening form * Claustrophobia…
Contacts

Alyssa Boudreau

214-456-2106

alyssa.boudreau@utsouthwestern.edu

CONTACT

Jeff Waugh, MD, PhD

214-867-6906

Jeff.Waugh@UTSouthwestern.edu

CONTACT