Assessment of Stroke Volume and Cardiac Output in Response to Varying Heart Rates
Recruiting
N/A
Interventional Study
Vasovagal Syncope
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
At a Glance
- Age
- 18 – 70
- Sex
- Any
- Study type
- Interventional
- Purpose
- Treatment
- Participants needed
- 25 (estimated)
- Sponsor
- University of Calgary · Other
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About This Trial
The investigators will seek to determine the effects of different heart rates on both stroke volume and cardiac output using non-invasive hemodynamic assessments. In order to safely manipulate the HR, the investigators will study patients with permanent pacemakers in whom heart rate manipulation can be done in a safe and non-invasive manner.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* Age 18-70 years (inclusive)
* Implanted permanent pacemaker or implanted defibrillator capable of atrial and ventricular pacing
* LV ejection fraction \>50%
Exclusion Criteria:
* Unable or unwilling to provide informed consent
* Clinical need for a cardiac resynchronization …
Contacts