Value of LNG-IUS as Fertility-preserving Treatment of EAH and EC

Recruiting Phase 2 Phase 3 Interventional Study
Endometrial Cancer Atypical Endometrial Hyperplasia
No Placebo Group Every participant receives an active treatment — no one gets a placebo. Pivotal Trial This treatment is in the last trial phase before FDA approval. Prior Safety Data This treatment has already been tested in at least one earlier human trial.
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At a Glance
Age
Up to 40
Sex
Female
Trial phase
Phase 2/3
Study type
Interventional
Purpose
Treatment
Participants needed
224 (estimated)
Sponsor
West China Second University Hospital · Other
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About This Trial

Primary end points: This clinical trial is aimed to analyze the effectiveness of Levonorgestrel-Releasing Intrauterine System (LNG-IUS, Mirena®) in the fertility-sparing treatment of atypical endometrial hyperplasia and early endometrial carcinoma, including pathology response and pregnancy outcome. Second end points: To analyze the appearances of side-effects.

Trial Locations
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Eligibility Criteria
For Patients With Endometrial Cancer: Inclusion Criteria: * ≤40 years of age: * Having a strong desire for fertility preservation; * Histological diagnosis is confirmed as well-differentiated (grade 1) endometrioid adenocarcinoma by the designated gynecological pathologists, and the progesterone r…
Contacts

ZHENG Ying, Professor

+8613018256012

935398163@qq.com

CONTACT

CHEN Si Jing, postgraduate

+86218380361314

Zhy_chd@126.com

CONTACT