DNA Methylation and Vascular Function
Recruiting
N/A
Interventional Study
Obesity
Vascular Dysfunction
No Placebo Group
Every participant receives an active treatment — no one gets a placebo.
Healthy Volunteers Welcome
You do not need to have the condition being studied to take part.
At a Glance
- Age
- 18 – 50
- Sex
- Any
- Study type
- Interventional
- Purpose
- Prevention
- Participants needed
- 80 (estimated)
- Sponsor
- University of Illinois at Chicago · Other
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About This Trial
The main objective is to examine DNA hypomethylation as an underlying mechanism for the increased production of inflammatory cytokines and the impaired vascular function in obese individuals and as a potential target for nonpharmacological preventive/therapeutic interventions such as aerobic exercise.
Trial Locations
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Eligibility Criteria
Inclusion Criteria:
* BMI ≥ 35 kg/m2
* Between ages 18-50 years
* Not pregnant
* Approved for a bariatric surgery
Exclusion Criteria:
* To avoid confounding from other inflammatory conditions individuals with current cancer, heart, kidney or liver disease, gallbladder disease or acute or chronic …
Contacts