Pharmacokinetics of Liposomal Amphotericin B in Critically Ill vs. Non-critically Ill Hematological Patients: Exploration of Covariates

Recruiting Observational Study
Pharmacokinetics Liposomal Amphotericin B Critically Ill Patients
No Placebo Group Every participant receives an active treatment — no one gets a placebo. No Study Drug Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 and older
Sex
Any
Study type
Observational
Participants needed
60 (estimated)
Sponsor
Universitaire Ziekenhuizen KU Leuven · Other
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About This Trial

This prospective study will compare the pharmacokinetic exposure to liposomal amphotericin B between critically ill patients and non-critically ill (hematology) patients in an early and late exposure day.

Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Treatment with L-AmB * Admitted to an ICU or Hematology ward Exclusion Criteria: * DNR 2 or 3 * Pregnant or lactating women * Previous documentation of intolerance/sensitivity to L-AmB
Contacts

Ruth Van Daele, PharmD

+3216343264

ruth.vandaele@uzleuven.be

CONTACT

Isabel Spriet, PharmD, PhD

+3216341261

isabel.spriet@uzleuven.be

CONTACT