Bariatric Surgery Impact on Venlafaxine Absorption
Bariatric Surgery and Pharmacokinetics of Venlafaxine
Recruiting
Observational Study
Obesity, Morbid
No Study Drug
Researchers observe your health over time — no experimental treatment is given.
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At a Glance
Age
18 – 70
Sex
Any
Study type
Observational
Participants needed
12 (estimated)
Sponsor
Norwegian University of Science and Technology · Other
Who this trial is looking for
This trial is looking for people who are planning to have gastric bypass or sleeve gastrectomy in Central Norway. Participants will help researchers understand how these surgeries affect the way the medication venlafaxine works in the body.
Are You a Good Fit for This Trial?
You may be able to join if
I am preparing to undergo gastric bypass or sleeve gastrectomy
I am a Norwegian citizen
You may not be able to join if
I have previously undergone resections in the GI-tract
Summarized in plain language from this trial's official eligibility criteria.
The full criteria are further down this page — only the research team can
confirm whether you qualify.
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Answer a few quick questions to see if you may meet the eligibility requirements.
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study th…
Changes to gastric pH, gastric emptying time, gastrointestinal transit-time or the pre-systemic metabolizing effect of enzymes secreted in the mucosa may all alter the pharmacokinetics of medicines. These factors are potentially influenced by bariatric surgery. Little is so far known about how gastric bypass and sleeve gastrectomy impacts the biological availability of medication. In this study the pharmacokinetic effects of bariatric surgery on venlafaxine are investigated.
Trial Locations
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Status
Eligibility Criteria
Inclusion Criteria:
* Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
* Being a Norwegian citizen
Exclusion Criteria:
* Having previously undergone resections in the GI-tract
Inclusion Criteria:
* Preparing to undergo gastric bypass or sleeve gastrectomy in Central Norway
* Being a Norwegian citizen
Exclusion Criteria:
* Having previously undergone resections in the GI-tract
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