Study of Coronary Calcium Score as a Marker of Post-radiation Vascular Dysplasia in Adults Treated During Childhood for Cancer With Mediastinal Irradiation

Recruiting N/A Interventional Study
Childhood Cancer
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
18 and older
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
500 (estimated)
Sponsor
Gustave Roussy, Cancer Campus, Grand Paris · Other
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About This Trial
To measure coronary calcium score in adults treated during childhood or adolescence for irradiation cancer in the heart and / or anthracycline area and compare them to determine whether irradiation of the heart area is associated with increased calcium score after adjustment for other cardiovascular risk factors (age, sex, smoking, dyslipidemia, obesity, diabetes, high blood pressure and renal fai…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: 1. Patients 18 years of age or older, 2. Treated for cancer during childhood, adolescence or young adulthood (≤25 years), 3. Treated with irradiation of the heart area (≥20% of ≥5Gy heart rate) and / or anthracycline (cumulative dose of doxorubicin equivalent ≥300mg/m\^²), 4. In…
Contacts

Brice FRESNEAU, MD

+33 (0)1 42 11 42 11

brice.fresneau@gustaveroussy.fr

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