Targeted Blood-pressure Management and Acute Kidney Injury After Coronary Artery Bypass Surgery

Recruiting N/A Interventional Study
Coronary Artery Bypass, Off-Pump Intraoperative Hypotension Acute Kidney Injury Preventive Medicine Intraoperative Care
No Placebo Group Every participant receives an active treatment — no one gets a placebo.
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At a Glance
Age
50 and older
Sex
Any
Study type
Interventional
Purpose
Prevention
Participants needed
612 (estimated)
Sponsor
Peking University First Hospital · Other
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About This Trial
Acute renal injury (AKI) is a common complication after cardiac surgery and is associated with worse outcomes. It is now realized that intraoperative hypotension is an important risk factor for the development of AKI. In a recent randomized controlled trial of patients undergoing major noncardiac surgery, intraoperative individualized blood-pressure management reduced the incidence of postoperativ…
Trial Locations
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Eligibility Criteria
Inclusion Criteria: * Age ≥ 50 years; * Scheduled to undergo off-pump CABG surgery. Exclusion Criteria: * Refuse to participate; * Untreated or uncontrolled severe hypertension (systolic blood pressure ≥180 mmHg or diastolic blood pressure ≥110 mmHg); * Chronic kidney disease with a glomerular fi…
Contacts

Dong-Xin Wang, MD, PhD

8610-83572784

wangdongxin@hotmail.com

CONTACT

Li Huang, MD, PhD

8610-83572460

huanglibd@163.com

CONTACT